rct
    2013

    Grape seed proanthocyanidin extract and venous oedema: randomized controlled evidence review

    Sano A, Tokutake S, Seo A

    Published in Phytotherapy Research

    Methodology

    Randomized placebo-controlled trial of grape seed proanthocyanidin extract on lower-leg oedema after prolonged sitting in healthy women.

    Key Findings

    Grape seed extract significantly reduced lower-leg swelling and circumference after prolonged sitting compared with placebo.

    Conclusions

    Grape seed proanthocyanidins reduce venous pooling and oedema.

    Limitations

    Small trial; healthy volunteers only.

    Supplements Studied

    Grape seed extract significantly reduced lower-leg swelling and circumference after prolonged sitting

    Outcomes Measured

    Grape seed extract significantly reduced lower-leg swelling and circumference after prolonged sitting compared with placebo

    Related Health Concerns

    Study Details

    Year:2013
    Sample Size:20
    Duration:2 weeks
    Quality Score:5/10

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