The use of methylsulfonylmethane-containing products in dermatology: an evidence-based systematic review of safety and efficacy

Dermatologic Therapy Review Group

Published in Dermatologic Therapy

Methodology

Systematic review of clinical studies of the organosulfur compound MSM in dermatologic applications.

Small trials suggest improvements in skin quality and rosacea symptoms; overall evidence quality is low.

Organosulfur supplementation shows preliminary dermatologic benefit but needs larger trials.

Few, small, often industry-linked studies.

Mineral

Organosulfur supplementation shows preliminary dermatologic benefit but needs larger trials.

Year:2026

Quality Score:5/10

This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.