Magnesium as a preventive treatment for paediatric episodic tension-type headache: results at 1-year follow-up
Grazzi L, et al
Published in Neurological Sciences
Methodology
Open, uncontrolled prospective cohort of paediatric patients with episodic tension-type headache given magnesium prophylaxis, with headache diary frequency and drug consumption assessed to 12 months.
Key Findings
Children with episodic tension-type headache treated with magnesium showed reduced headache frequency and analgesic use maintained at one-year follow-up, though the improvement occurred without a control group.
Conclusions
Uncontrolled findings are encouraging and suggest better controlled research on magnesium for paediatric tension-type headache is warranted.
Limitations
No placebo or control arm, open-label design highly susceptible to placebo effect and natural remission in paediatric headache, and modest sample (n=45).
Supplements Studied
Although uncontrolled, these findings are encouraging and suggest that further, better controlled research investigations are warranted.
Related Health Concerns
Study Details
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