Systematic review and meta-analysis of the effect of zinc on wound healing
Arribas Lopez E, Zand N, Ojo O, Kochhar T
Published in BMJ Nutrition, Prevention & Health
Methodology
Systematic review and meta-analysis of five clinical trials of zinc treatment for wound and ulcer healing, GRADE assessed
Key Findings
Zinc treatment was associated with improved ulcer healing at final endpoint (MD 1.41, 95% CI 1.04 to 1.92, p = 0.03), graded as moderate quality evidence.
Conclusions
Zinc may improve ulcer healing, though the underlying trials are few and limited.
Limitations
Only five small trials met inclusion criteria; heterogeneous wound types and zinc routes; moderate GRADE quality.
Supplements Studied
The meta-analysis suggested that zinc treatment may be associated with improvements in ulcers healing at the final endpoint MD: 1.41 (95% CI 1.04, 1.92, p = 0.03).
Outcomes Measured
Zinc treatment may be associated with improvements in ulcer healing at the final endpoint.
The meta-analysis suggested that zinc treatment may be associated with improvements in ulcers healing at the final endpoint MD: 1.41 (95% CI 1.04, 1.92, p = 0.03).
Study Details
Access Study
Disclosures
Funding
Academic/institutional
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.