Effectiveness of high-dose riboflavin in migraine prophylaxis: a randomized controlled trial
Schoenen J, Jacquy J, Lenaerts M
Published in Neurology
Methodology
Randomised placebo-controlled trial of riboflavin 400 mg daily for three months in 55 adults with migraine.
Key Findings
Riboflavin was superior to placebo for attack frequency and headache days, with 59% versus 15% achieving at least 50% reduction in attacks.
Conclusions
High-dose riboflavin is an effective and well-tolerated migraine prophylactic.
Limitations
Single centre, modest sample, three-month duration.
Supplements Studied
Riboflavin was superior to placebo, with 59% versus 15% of patients achieving at least a 50% reduction in attacks.
Outcomes Measured
59% of riboflavin patients versus 15% on placebo achieved at least 50% reduction in attacks.
Related Health Concerns
Study Details
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