Prophylaxis of migraine headaches with riboflavin: a systematic review

Thompson DF, Saluja HS

Published in Journal of Clinical Pharmacy and Therapeutics

Methodology

Systematic review of 11 clinical trials of riboflavin for migraine prophylaxis in adults and children.

Adult trials generally showed reduced attack frequency at 400 mg daily, whereas paediatric trials were largely negative.

Riboflavin appears useful for adult migraine prophylaxis but the evidence in children does not support benefit.

Heterogeneous dosing and outcome definitions; several small open studies included.

Vitamin

Adult trials generally showed reduced attack frequency at 400 mg daily, whereas paediatric trials were largely negative.

Year:2017

Duration:12 weeks

Quality Score:7/10

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