rct
2019
High Quality
Topical glycopyrronium tosylate for the treatment of primary axillary hyperhidrosis: ATMOS-1 and ATMOS-2 phase 3 randomized controlled trials
Glaser DA, Hebert AA, Nast A, Werschler WP, Green L, Mamelok R, Quiring J, Pariser DM
Published in Journal of the American Academy of Dermatology
Key Findings
Topical glycopyrronium produced significantly greater reductions in sweat production and severity scores than vehicle over 4 weeks.
Conclusions
Topical anticholinergic therapy is an effective, well-tolerated option for axillary hyperhidrosis.
Limitations
Industry-funded, short duration, anticholinergic side effects.
Related Health Concerns
Study Details
Year:2019
Sample Size:697
Duration:4 weeks
Quality Score:8/10
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