rct
    2019
    High Quality

    Topical glycopyrronium tosylate for the treatment of primary axillary hyperhidrosis: ATMOS-1 and ATMOS-2 phase 3 randomized controlled trials

    Glaser DA, Hebert AA, Nast A, Werschler WP, Green L, Mamelok R, Quiring J, Pariser DM

    Published in Journal of the American Academy of Dermatology

    Key Findings

    Topical glycopyrronium produced significantly greater reductions in sweat production and severity scores than vehicle over 4 weeks.

    Conclusions

    Topical anticholinergic therapy is an effective, well-tolerated option for axillary hyperhidrosis.

    Limitations

    Industry-funded, short duration, anticholinergic side effects.

    Related Health Concerns

    Study Details

    Year:2019
    Sample Size:697
    Duration:4 weeks
    Quality Score:8/10

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