crossover
    1996

    Zinc status and serum sex hormone binding globulin in men: a controlled dietary restriction study

    Prasad AS, Mantzoros CS, Beck FW, Hess JW, Brewer GJ

    Published in Nutrition

    Methodology

    Controlled dietary zinc restriction and repletion study in healthy young men measuring serum testosterone and binding proteins.

    Key Findings

    Marginal zinc deficiency markedly reduced serum testosterone, and repletion restored it in older marginally deficient men.

    Conclusions

    Zinc adequacy is required for normal androgen and binding-protein balance.

    Limitations

    Very small sample; older non-randomised design.

    Supplements Studied

    Zinc
    Mineral

    Marginal zinc deficiency markedly reduced serum testosterone, and repletion restored it

    Outcomes Measured

    Sex Hormone Binding Globulin

    Marginal zinc deficiency markedly reduced serum testosterone, and repletion restored it

    Study Details

    Year:1996
    Sample Size:40
    Duration:20 weeks
    Quality Score:4/10

    Access Study

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