rct
    2006

    Comparison of Pycnogenol and Daflon in treating chronic venous insufficiency: a prospective, controlled study

    Cesarone MR, Belcaro G, Rohdewald P, Pellegrini L, Ledda A, Vinciguerra G, Ricci A, Gizzi G, Ippolito E, Fano F, Dugall M, Acerbi G, Cacchio M, Di Renzo A, Hosoi M, Stuard S, Corsi M

    Published in Clinical and Applied Thrombosis/Hemostasis

    Methodology

    Prospective controlled study comparing Pycnogenol with Daflon for symptoms and edema of chronic venous insufficiency over 8 weeks

    Key Findings

    Pycnogenol produced greater reductions in leg edema and symptom scores than Daflon in this comparison

    Conclusions

    Pycnogenol may relieve symptoms of chronic venous insufficiency

    Limitations

    Open comparative design; investigator group with commercial ties

    Supplements Studied

    Pycnogenol produced greater reductions in leg edema and symptom scores than Daflon in this comparison

    Related Health Concerns

    Study Details

    Year:2006
    Sample Size:86
    Duration:8 weeks
    Quality Score:4/10

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