Curcumin for the treatment of major depression: a randomised, double-blind, placebo controlled study
Lopresti AL, Hood SD, Drummond PD
Published in Journal of Affective Disorders
Methodology
Randomized double-blind placebo-controlled 8-week trial of curcumin 500 mg twice daily in adults with major depressive disorder
Key Findings
Curcumin and placebo were comparable through week 4, after which curcumin produced significantly greater improvement in mood, particularly in atypical depression
Conclusions
Curcumin showed modest antidepressant benefit emerging after four weeks
Limitations
Small sample; short duration; single site
Supplements Studied
Curcumin produced significantly greater mood improvement than placebo after week four, especially in atypical depression
Curcumin and placebo were comparable through week 4, after which curcumin produced significantly greater improvement in mood, particularly in atypical depression
Outcomes Measured
Curcumin produced significantly greater mood improvement than placebo after week four
Related Health Concerns
Study Details
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