The effect of zinc lozenge on postoperative sore throat: a prospective randomized, double-blinded, placebo-controlled study

Farhang B, Grondin L

Published in Anesthesia and Analgesia

Methodology

Randomized double-blinded placebo-controlled trial of a 40 mg zinc lozenge 30 minutes before intubation, with sore throat assessed to 24 hours

Postoperative sore throat at 4 hours was lower with zinc (7%) than placebo (29%, P = .046), with lower incidence at 0 and 2 hours as well

A single preoperative zinc lozenge reduced intubation-related sore throat

Small single-centre trial, intubation-specific setting, short follow-up

Mineral

At 4 hours, there was a significantly lower incidence of POST in the zinc group, 7%, than the control group, 29% (P = .046).

Year:2018

Sample Size:79

Duration:1 weeks

Quality Score:7/10

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