Effect of supplementation with marine omega-3 fatty acid on risk of colorectal adenomas and serrated polyps in the US general population
Song M, Lee IM, Manson JE, Buring JE, Dushkes R
Published in JAMA Oncology
Methodology
Prespecified ancillary analysis of the placebo-controlled VITAL randomized trial of 1 g/day marine omega-3 over a median 5.3 years
Key Findings
Marine omega-3 supplementation did not reduce overall risk of conventional adenomas or serrated polyps in the general population
Conclusions
Omega-3 supplements do not prevent colorectal cancer precursors overall
Limitations
Endoscopy ascertainment limited to reported procedures, single dose tested, subgroup findings exploratory
Supplements Studied
Marine ω-3 fatty acid, 1 g daily (which included eicosapentaenoic acid, 460 mg, and docosahexaenoic acid, 380 mg)
Related Health Concerns
Study Details
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Disclosures
Funding
National Institutes of Health
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.