systematic_review
    2024

    Apigenin: a natural molecule at the intersection of sleep and aging

    Kramer DJ, Johnson AA

    Published in Frontiers in Nutrition

    Key Findings

    Reviews evidence that apigenin binds GABA-A benzodiazepine sites and modulates sleep and aging pathways, with human data limited largely to chamomile preparations.

    Conclusions

    Apigenin is a plausible sleep- and longevity-relevant flavonoid, but direct human trials of isolated apigenin are lacking.

    Limitations

    Narrative review; extrapolates heavily from preclinical and whole-extract data.

    Supplements Studied

    Apigenin
    Compound

    Apigenin: a natural molecule at the intersection of sleep and aging.

    Reviews evidence that apigenin binds GABA-A benzodiazepine sites and modulates sleep and aging pathways, with human data limited largely to chamomile preparations.

    Related Health Concerns

    Insomnia

    Study Details

    Year:2024
    Quality Score:4/10

    Access Study

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