L-carnitine supplementation, muscle carnitine content and fuel metabolism during exercise
Wall BT, Stephens FB, Constantin-Teodosiu D, Marimuthu K, Macdonald IA, Greenhaff PL
Published in Journal of Physiology
Methodology
Randomized controlled trial of chronic carnitine plus carbohydrate feeding with muscle biopsies assessing carnitine content and substrate use.
Key Findings
Carnitine feeding raised muscle carnitine content and altered fuel selection, sparing glycogen at low intensity and increasing work output.
Conclusions
Raising muscle carnitine improves substrate switching between fat and carbohydrate.
Limitations
Requires high carbohydrate co-ingestion and 12+ weeks; small sample.
Supplements Studied
Carnitine feeding raised muscle carnitine content and altered fuel selection
Outcomes Measured
Carnitine feeding raised muscle carnitine content and altered fuel selection, sparing glycogen at low intensity
Study Details
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