A two-year follow-up of oral antioxidant supplementation in primary open-angle glaucoma: an open-label, randomized, controlled trial
Garcia-Medina JJ, Garcia-Medina M, Garrido-Fernandez P, Zanon-Moreno V, Pinazo-Duran MD
Published in Acta Ophthalmologica
Methodology
Open-label randomized controlled trial of oral antioxidant supplementation added to standard IOP-lowering treatment versus standard treatment alone over two years in POAG
Key Findings
Antioxidant-supplemented patients showed improved oxidative stress biomarkers but no significant difference in visual field indices or structural progression
Conclusions
Oral antioxidants improved biochemical markers without a clear clinical benefit on visual field progression
Limitations
Open-label design; biochemical endpoints emphasised; single-country sample
Related Health Concerns
Study Details
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Disclosures
Funding
Spanish institutional support
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