Role of vinpocetine in cerebrovascular diseases
Patyar S, Prakash A, Modi M, Medhi B
Published in Pharmacological Reports
Methodology
Review of pharmacology, cerebral blood flow effects and the clinical trial record for vinpocetine in cerebrovascular disease.
Key Findings
Vinpocetine increases cerebral blood flow and has anti-inflammatory and neuroprotective actions in models, but human outcome data remain limited and largely from older trials.
Conclusions
Mechanistic plausibility exceeds the quality of the available clinical evidence.
Limitations
Narrative review; no formal bias assessment or pooling.
Supplements Studied
Vinpocetine increases cerebral blood flow and has neuroprotective actions, but clinical outcome data remain limited.
Outcomes Measured
Vinpocetine increases cerebral blood flow and has anti-inflammatory and neuroprotective actions in models, but human outcome data remain limited and largely from older trials.
Study Details
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