Effects of lutein/zeaxanthin supplementation on the cognitive function of community dwelling older adults: a randomized, double-masked, placebo-controlled trial
Hammond BR, Miller LS, Bello MO, Lindbergh CA, Mewborn C, Renzi-Hammond LM
Published in Frontiers in Aging Neuroscience
Methodology
Randomised double-masked placebo-controlled trial of 12 mg/day lutein and zeaxanthin for 12 months in community-dwelling older adults.
Key Findings
Supplemented participants showed improved complex attention and cognitive flexibility relative to placebo, with gains correlated to increases in macular pigment optical density.
Conclusions
Lutein and zeaxanthin supplementation may modestly support specific cognitive domains in older adults.
Limitations
Small sample; multiple cognitive endpoints raising type I error risk; healthy volunteers only.
Supplements Studied
Supplemented older adults showed improved complex attention and cognitive flexibility relative to placebo.
Supplemented participants showed improved complex attention and cognitive flexibility relative to placebo, with gains correlated to increases in macular pigment optical density.
Outcomes Measured
Supplemented older adults showed improved complex attention and cognitive flexibility relative to placebo.
Study Details
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