Non-digestible carbohydrate and the risk of colorectal neoplasia: a systematic review
Rao M, Gao C, Hou J, Gu J, Law BYK
Published in Nutrition and Cancer
Methodology
Systematic review and meta-analysis of resistant starch and inulin supplementation trials assessing short-chain fatty acids and colorectal neoplasia risk
Key Findings
Resistant starch and inulin supplementation did not significantly increase faecal short-chain fatty acid or butyrate levels, and clinical chemoprevention evidence was inconsistent
Conclusions
Fibre-type supplements have not been shown to reduce colorectal neoplasia risk
Limitations
Heterogeneous interventions and outcomes, few clinical endpoint trials, short durations
Supplements Studied
the total SCFAs and butyrate concentrations (P = 0.84; P = 0.79), and excretions (P = 0.55; P = 0.63) in feces did not increase significantly after RS/inulin supplementation
Related Health Concerns
Study Details
Access Study
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.