rct
    2015
    High Quality

    Efficacy and safety of N-acetylcysteine in prevention of noise induced hearing loss: a randomized clinical trial

    Kopke R, Slade MD, Jackson R, Hammill T, Fausti S, Lonsbury-Martin B, Sanderson A, Dreisbach L, Rabinowitz P, Torre P, Balough B

    Published in Hearing Research

    Key Findings

    NAC did not significantly reduce the rate of standard threshold shift after weapons training; only secondary analyses hinted at benefit.

    Conclusions

    N-acetylcysteine failed to prevent noise-induced hearing loss on its primary endpoint.

    Supplements Studied

    The null hypothesis for the rate of STS was not rejected based on the measured results. While no significant differences were found for the primary outcome, rate of threshold shifts, the present study design failed to confirm this.

    Related Health Concerns

    Hearing Loss

    Study Details

    Year:2015
    Sample Size:566
    Quality Score:8/10

    Access Study

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