meta_analysis
    2021

    Evaluation of Clinical Meaningfulness of Red Clover (Trifolium pratense L.) Extract to Relieve Hot Flushes and Menopausal Symptoms in Peri- and Post-Menopausal Women: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

    Kanadys W, Baranska A, Blaszczuk A, Polz-Dacewicz M, Drop B, Kanecki K, Malm M

    Published in Nutrients

    Key Findings

    Red clover isoflavones significantly reduced daily hot flush frequency versus placebo, with a modest and arguably borderline clinically meaningful effect size.

    Conclusions

    Red clover produces a small reduction in hot flushes of uncertain clinical importance.

    Limitations

    Small trials, varied extracts and doses, publication bias possible.

    Supplements Studied

    Red clover isoflavones significantly reduced daily hot flush frequency versus placebo, with a modest effect size.

    Outcomes Measured

    Red clover isoflavones reduced daily hot flush frequency with a modest effect size.

    Related Health Concerns

    Study Details

    Year:2021
    00
    Quality Score:6/10

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