Impact of peppermint therapy on dysphagia and non-cardiac chest pain: a pilot study
Khalaf MHG, et al.
Published in Digestive Diseases and Sciences
Methodology
Single-centre pilot cohort study of patients with dysphagia and/or non-cardiac chest pain treated with peppermint oil, with symptom response assessed against baseline high-resolution manometry findings.
Key Findings
Peppermint oil produced symptomatic relief in a subset of patients with dysphagia and non-cardiac chest pain; response was more likely in those with a defined manometric disorder such as distal esophageal spasm or esophagogastric junction outflow obstruction.
Conclusions
PO appears to provide symptomatic relief in some patients with dysphagia and CP. Presence of a well-defined manometric disorder, particularly DES or EGJOO, appeared to predict response.
Limitations
Small uncontrolled pilot (n=38) with no placebo arm, subjective symptom endpoints and potential selection bias.
Supplements Studied
PO appears to provide symptomatic relief in some patients with dysphagia and CP.
Related Health Concerns
Study Details
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